CALIFORNIA LEGISLATURE— 2025–2026 REGULAR SESSION

99

Introduced by Assembly Member Nguyen

(Coauthors: Assembly Members Aguiar-Curry, Ahrens, Alanis, Arambula, Ávila Farías, Bauer-Kahan, Bennett, Berman, Boerner, Bonta, Calderon, Caloza, Castillo, Chen, Connolly, Davies, DeMaio, Fong, Gabriel, Garcia, Gipson, Jeff Gonzalez, Mark González, Hadwick, Haney, Harabedian, Hart, Hoover, Irwin, Jackson, Johnson, Kalra, Krell, Lackey, Lee, Lowenthal, Macedo, McKinnor, Muratsuchi, Ortega, Pacheco, Papan, Patel, Patterson, Pellerin, Petrie-Norris, Quirk-Silva, Ramos, Ransom, Rivas, Michelle Rodriguez, Rogers, Blanca Rubio, Sanchez, Schiavo, Schultz, Sharp-Collins, Solache, Stefani, Ta, Tangipa, Valencia, Wallis, Ward, Wicks, Wilson, and Zbur)

February 12, 2026

Relative to Angelman Syndrome Awareness Day.

WHEREAS, Angelman syndrome is a rare neurogenetic disorder that occurs in 1 in 15,000 live births and affects approximately 500,000 individuals worldwide; and

WHEREAS, Angelman syndrome is caused by a loss of function of the UBE3A gene in chromosome 15 derived from the mother, and a gene that is needed to develop and control speech and movement; and

WHEREAS, Individuals with Angelman syndrome begin experiencing developmental delays starting from 6 and 12 months of age, inclusive, and these developmental delays are often the first signs of Angelman syndrome; and

WHEREAS, In addition to delayed development, Angelman syndrome causes problems with speech and balance, mental disability, and sometimes seizures; and

WHEREAS, Angelman syndrome shares symptoms and characteristics with other disorders, including autism, cerebral palsy, and Prader-Willi syndrome; and

WHEREAS, Individuals with Angelman syndrome have an overall happy and excitable demeanor, and they smile and laugh often; and

WHEREAS, Angelman syndrome is rare. Most individuals with Angelman syndrome do not have a family history of the syndrome, and researchers often do not know what causes the genetic changes that result in the disease; and

WHEREAS, Angelman syndrome can lead to several complications, including trouble feeding, hyperactivity, sleep troubles, scoliosis, and obesity; and

WHEREAS, The treatment of Angelman syndrome focuses on managing medical, sleep, and developmental issues; and

WHEREAS, There is currently no cure for Angelman syndrome, but organizations such as the Angelman Syndrome Foundation note that with further research, there may be a cure in the future; and

WHEREAS, Organizations worldwide recognize February 15 as International Angelman Day to raise awareness about Angelman syndrome; now, therefore, be it

Resolved by the Assembly of the State of California, That the Assembly hereby recognizes February 15, 2026, as Angelman Syndrome Awareness Day; and be it further

Resolved, That the Chief Clerk of the Assembly transmit copies of this resolution to the author for appropriate distribution.